More vitamin D may improve memory but too much may slow reaction time

How much vitamin D can boost memory, learning and decision-making in older adults, and how much is too much?

A unique Rutgers-led study found that overweight and obese older women who took more than three times the recommended daily dose of vitamin D showed improvements in memory and learning — but also had slower reaction times. The researchers hypothesize that slower reaction times may increase the risk of falling among older people, according to Science Daily.

The researchers, used computers to assess the impact of vitamin D on cognitive function. The researchers evaluated three groups of women between 50 and 70 years old in a randomized controlled trial.

One group took the recommended daily dose of 600 international units (IU), equivalent to 15 micrograms, of vitamin D each day for a year. Another group took 2,000 IU per day and the third took 4,000. All women participated in lifestyle counseling and were encouraged to lose a modest amount of weight.

The researchers found that memory and learning improved in the group that took 2,000 IU per day, but not in the group that took the higher dosage. Meanwhile, the women’s reaction time showed a trend to be slower at 2,000 IU daily and was significantly slower at the higher dosage.

“The slower reaction time may have other negative outcomes such as potentially increasing the risk of falling and fractures,” said senior author Sue Shapses, a professor. “This is possible since other researchers have found that vitamin D supplementation at about 2,000 IU daily or more increased risk of falls, but they did not understand the cause. Our team’s findings indicating a slower reaction time may be one answer. Many people think that more vitamin D supplementation is better, but this study shows that is not always the case.”

Shapses said 4,000 IU a day might not be a problem for younger people but for the elderly it could compromise walking or catching one’s balance to avoid a fall because their reaction time is slower. This is a presumption until future research can cover vitamin D levels, cognition and falls in one study, she added.

Vitamin D — known for its importance for bone health — is obtained through sun exposure and some foods. Researchers have also found that vitamin D has a major impact on how the body, including the brain, functions.

Cognitive impairment and dementia are significant public health problems, especially with aging, the study notes. Evidence shows that vitamin D plays a role in cognition and the normal functioning of the central nervous system.

More research is needed to determine whether reaction time is related to rates of falls and injuries in at-risk populations. Examining different doses of vitamin D supplementation and from dietary sources in both men and women of different ages, and people of different races over a longer period, also needs to be studied, Shapses said. Larger studies are needed as well.

N.H.Kh