Two workers die  while maintaining the sewage network in Hasakeh

Two workers die while maintaining the sewage network in Hasakeh

Hasakeh (ST): Two workers died today of...

Maduro announces  readiness to negotiate with the opposition

Maduro announces readiness to negotiate with the opposition

Caracas (ST): Venezuelan President Nicolas...

Cuba denounces the new US sanctions targeting it

Cuba denounces the new US sanctions targeting it

Havana (ST): Cuba denounced the sanctions...

Mexico records the highest number of Corona infections  since January

Mexico records the highest number of Corona infections since January

Mexico City (ST): Mexico recorded the highest...

“A Flicker in the Andes” a new novel by the writer Ahlam  Abu Assaf

“A Flicker in the Andes” a new novel by the writer Ahlam Abu Assaf

Damascus (ST): A Flicker in the Andes Mountains...

Israeli warplanes renew their violation of Lebanese airspace

Israeli warplanes renew their violation of Lebanese airspace

Beirut (ST): Israeli warplanes renewed their...

Homs artists  hold an exhibition of roses in Sobhi Shuaib hall

Homs artists hold an exhibition of roses in Sobhi Shuaib hall

Homs (ST): Because flowers and roses are a...

Zakharova: OPCW falsified reported about alleged Douma incident

Zakharova: OPCW falsified reported about alleged Douma incident

MOSCOW, (ST)_Russian Foreign Ministry...

  • In memory of Maysaloun: People's Assembly affirm Syrian people are neither faint nor weak, no matter how severe the tribulations

    In memory of Maysaloun: People's Assembly...

    Friday, 23 July 2021 16:48
  • Two workers die  while maintaining the sewage network in Hasakeh

    Two workers die while maintaining the sewage...

    Friday, 23 July 2021 13:22
  • 13 Palestinian prisoners continue their hunger strike to protest the crimes of the occupation

    13 Palestinian prisoners continue their hunger...

    Friday, 23 July 2021 13:18
  • Dozens of Palestinians injured as a result of the occupation’s suppression of a demonstration east of Nablus

    Dozens of Palestinians injured as a result of...

    Friday, 23 July 2021 13:14
  • Former Turkish Ambassador: Erdogan’s Brotherhood doctrine has led Turkey to a deadlock

    Former Turkish Ambassador: Erdogan’s...

    Friday, 23 July 2021 13:09
  • On the anniversary of the TV foundation: Minister Sara: Syrian TV has remained a screen for the homeland and the voice of all Syrians

    On the anniversary of the TV foundation:...

    Friday, 23 July 2021 12:28
  • Maduro announces  readiness to negotiate with the opposition

    Maduro announces readiness to negotiate with...

    Friday, 23 July 2021 09:04
  • Cuba denounces the new US sanctions targeting it

    Cuba denounces the new US sanctions targeting it

    Friday, 23 July 2021 09:01
  • A Palestinian was shot by the occupation forces and eight others arrested in the West Bank

    A Palestinian was shot by the occupation forces...

    Friday, 23 July 2021 08:56
  • Mexico records the highest number of Corona infections  since January

    Mexico records the highest number of Corona...

    Friday, 23 July 2021 08:49
  • “A Flicker in the Andes” a new novel by the writer Ahlam  Abu Assaf

    “A Flicker in the Andes” a new novel by the...

    Friday, 23 July 2021 08:44
  • Moon Celebration,  a variety of artistic activities for children held in Lattakia

    Moon Celebration, a variety of artistic...

    Friday, 23 July 2021 08:29
  • An American-Iraqi agreement on the withdrawal of American forces from Iraq by the end of the year

    An American-Iraqi agreement on the withdrawal...

    Friday, 23 July 2021 08:24
  • Israeli warplanes renew their violation of Lebanese airspace

    Israeli warplanes renew their violation of...

    Friday, 23 July 2021 08:20
  • Palestinian FM welcomes the formation of a commission of inquiry into the Israeli aggression

    Palestinian FM welcomes the formation of a...

    Friday, 23 July 2021 08:13
  • Homs artists  hold an exhibition of roses in Sobhi Shuaib hall

    Homs artists hold an exhibition of roses in...

    Friday, 23 July 2021 08:07
  • Zakharova: OPCW falsified reported about alleged Douma incident

    Zakharova: OPCW falsified reported about...

    Thursday, 22 July 2021 19:41
  • Lavrov hopes that new round of Syrian constitutional talks will be held in Geneva soon

    Lavrov hopes that new round of Syrian...

    Thursday, 22 July 2021 18:29
  • The goals of the so-called “autonomous administration” are to weaken Syria and serve US and Turkish occupiers-FM

    The goals of the so-called “autonomous...

    Thursday, 22 July 2021 18:04
  • Facts point to interaction between US, ISIS in Afghanistan — Russian  diplomat

    Facts point to interaction between US, ISIS in...

    Thursday, 22 July 2021 16:08

Economy & Aftermath

Investigative Reporting

SCS branch in Lattakia holds the first exhibition of modeling and simulation projects

SCS branch in Lattakia holds the first e…

The  Syrian Computer Society ( SCS) branch in Lattakia has recently held  the first exhibition of modeling and simulation projects, which  includes 11 projects presented ...

  1. Tourism
  2. Culture
  3. Society
  4. Golan
Preparations have begun for the “Victory Celebration” of the “Citadel and Valley” Festival 2021

Preparations have begun for the “Victory…

Under the patronage Prime Minister Hussein Arnous, Homs Governorate, in cooperation with the Ministries of Tourism and Culture, began preparations for the “victory celebration” of the "Citadel and Valley" festival 2021, after it had stopped for a year due to the outbreak of Covid-19  pandemic.    Homs Governor, Eng. Bassam Parsik, said in a meeting recently held that the “Citadel and Valley”  Festival ["Al-Qal'a Wa...

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Activities for kids are organized in the 41st  Flowers Expo in Damascus

Activities for kids are organized in the…

DAMASCUS, (ST)_Ministries of Tourism and Culture have organized activities and stage plays for kids and youths in the 41st session of Flowers Expo in Tishreen Park in Damascus.    The activities include Folk dances and plays, according to Director od Damascus Tourism Bassam Mardini, who said that the show is an opportunity to encourage popular tourism. 

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Two ladies make sweets at their home to support their families

Two ladies make sweets at their home to …

TARTOUS, (ST)_With the aim of supporting their families, two ladies, Sawsan Wardeh and Imtithal Abbas, from Banias countryside in Tartous province make sweets at their home upon orders they receive from local residents in their area.    The two ladies have started their micro-project three years ago , according to the Syrian News Agency (SANA), which affirmed that the prices of the sweets being made by two breadwinners are low compared to the p...

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Syrians celebrate the anniversary of hoisting national flag in liberated Quneitra city

Syrians celebrate the anniversary of hoi…

QUNEITRA, (ST)_ The province of Quneitra  has celebrated the anniversary of hoisting the Syrian flag in the liberated Quneitra on June, 26, 1974, according to the Syrian News Agency (SANA).    The agency reported on Thursday that a celebration was held in Al-Tahrir square in the liberated Quneitra city where speakers asserted that  the October War was and still is  the gate for completing the liberation of the occu...

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Our immune cells can sometimes recognize and destroy cancer cells without assistance. But tumors may hide from the immune system by taking advantage of a gene called CD47.

Normally, the gene makes a protein that studs the surface of red blood cells, a kind of sign that reads, “Don’t Eat Me.” Immune cells see it, and pass by healthy red blood cells.

But as red blood cells age, they lose CD47 proteins. Eventually the immune cells no longer give them a free pass, gobbling up old cells to make way for new ones.

Mutations in cancer cells can cause them to switch on the CD47 gene. The immune system sees these cells, too, as harmless, allowing them to grow into dangerous tumors.

In recent years, scientists have been developing antibodies that can attach to CD47 proteins on cancer cells, masking the “Don’t Eat Me” sign. Then the body’s immune cells learn to recognize the cancer cells as dangerous and attack.

But standard antibodies are big molecules that can’t burrow into a large tumor. And since they have to be injected into the bloodstream, these antibodies end up everywhere in the body, causing side effects.

 Bacteria cannot make normal antibodies for CD47. But recently, Doctors developed a tiny version of the molecule called a nanobody.

Not only are nanobodies small enough for bacteria to produce, they’re also much more potent than conventional antibodies.

The researchers inserted the nanobody gene into the bacteria, turning them into nanobody factories. Then the team injected five million of the altered microbes into mouse tumors.

The bacteria were also programmed to commit mass suicide. After they established themselves and multiplied, 90 percent of the bacteria ripped themselves apart, spilling out nanobodies.

The nanobodies attached to CD47 proteins on the cancer cells, robbing them of their camouflage.

In addition, fragments of the dead bacteria leaked out of the tumor. These bits of debris drew the attention of immune cells, which attacked the uncloaked cancer cells.

When Doctors originally developed their CD47 nanobody, they recognized that transporting it to cancer cells would be crucial to its effectiveness. But he never imagined that someone would hide it inside a microbial Trojan Horse.

Doctors cautioned that the genetically reprogrammed bacteria might not be as powerful in people as they seem to be in mice.

“We have basically the same plumbing, but just on a much larger scale,” they said. “What that means is that stuff doesn’t as efficiently move from one part of a person to another.”

“These things are not just seen as crazy things to play with,” said Doctors. “They potentially could actually make their way into patients.”

 

Lara Khouli