lzheimer's Disease in Mice Alleviated: Promising Therapeutic Approach for Humans

Pathological changes typical of Alzheimer's disease were significantly reduced in mice by blockade of an immune system transmitter. A research team from Charité – Universitäts medizin Berlin and the University of Zurich has just published a new therapeutic approach in fighting Alzheimer's disease in the current issue of Nature Medicine. This approach promises potential in prevention, as well as in cases where the disease has already set in.

Alzheimer's disease is one of the most common causes of dementia. In Germany and Switzerland alone, around 1.5 million people are affected, and forecasts predict a doubling of the number of patients worldwide within the next 20 years. The accumulation of particular abnormal proteins, including amyloid-ß (Aβ) among others, in patients' brains plays a central role in this disease. Prof. Frank Heppner from the Department of Neuropathology at Charité and his colleague Prof. Burkhard Becher from the Institute for Experimental Immunology at the University of Zurich were able to show that turning off particular cytokines (immune system signal transmitters) reduced the Alzheimer's typical amyloid-ß deposits in mice with the disease. As a result, the strongest effects were demonstrated after reducing amyloid-ß by approximately 65 percent, when the immune molecule p40 was affected, which is a component of the cytokines interleukin (IL)-12 and -23.

Relevant for human therapy

Follow-up experiments also relevant for humans showed that substantial improvements in behavioral testing resulted when mice were given the antibody blocking the immune molecule p40. This effect was also achieved when the mice were already showing symptoms of the disease. Based on the current study by Prof. Heppner's and Prof. Becher's team, the level of p40 molecules is higher in Alzheimer's patients' brain fluid, which is in agreement with a recently published study by American colleagues demonstrating increased p40 levels in blood plasma of subjects with Alzheimer's disease, thus showing obvious relevance for human therapy, according to Science Daily.

National Vaccination Campaign Launched Today

DAMASCUS,(ST)_ Some 2.5 million under-five year old children  will benefit from the national vaccination campaign  which  was launched  on Monday (today)  through December 6th , in 1816 health centers  distributed across Syria, the ministry of health reported on Monday.

The vaccines covered common children diseases   as ; Cough, Diarrhea, flu and Jaundice, according to Ministry 's director of health care department Dr.  Ahmad Al-abboud.

In Damascus, the campaign   was launched Monday targeting   200 children in 59 health centers in 8 areas , said head of Damascus Health Department Dr. Imad Jamil.

It is worth noting that the national vaccination campaign is carried out in collaboration between several ministries concerned, people's organizations, the Syrian Red Crescent Society, UNICEF, the World Health Organization WHO and UNRWA.


Laughter, key of happiness

Research has shown that the health benefits of laughter are far-ranging. While more studies need to be done, studies so far have shown that laughter can help relieve pain, bring greater happiness, and even increase immunity. Positive psychology names the propensity for laughter and sense of humor as one of the 24 main signature strengths one can possess, and laughter yoga clubs are springing up across the country.

Unfortunately, however, many people don't get enough laugher in their lives. In fact, one study suggests that healthy children may laugh as much as 400 ties per day, but adults tend to laugh only 15 times per day.

 Read on for more findings about the health benefits of laughter, and see how to incorporate more humor and fun into your life.

Stress Management Benefits of Laughter:


 Laughter reduces the level of stress hormones like cortisol, epinephrine (adrenaline), dopamine and growth hormone. It also increases the level of health-enhancing hormones like endorphins, and neurotransmitters. Laughter increases the number of antibody-producing cells and enhances the effectiveness of T cells. All this means a stronger immune system, as well as fewer physical effects of stress.

•Physical Release

 Have you ever felt like you "have to laugh or I'll cry"? Have you experienced the cleansed feeling after a good laugh? Laughter provides a physical and emotional release.

 •Internal Workout

A good belly laugh exercises the diaphragm, contracts the abs and even works out the shoulders, leaving muscles more relaxed afterward. It even provides a good workout for the heart.


Laughter brings the focus away from anger, guilt, stress and negative emotions in a more beneficial way than other mere distractions.


Studies show that our response to stressful events can be altered by whether we view something as a 'threat' or a 'challenge'. Humor can give us a more lighthearted perspective and help us view events as 'challenges', thereby making them less threatening and more positive. (For more on changing your perspective, see this article on cognitive reframing.)

•Social Benefits of Laughter:

Laughter connects us with others. Just as with smiling and kindness, most people find that laughter is contagious, so if you bring more laughter into your life, you can most likely help others around you to laugh more, and realize these benefits as well. By elevating the mood of those around you, you can reduce their stress levels, and perhaps improve the quality of social interaction you experience with them, reducing your stress level even more!

How To Use Laughter

Laughter is one of my all-time favorite stress management strategies because it's free, convenient, and beneficial in so many ways. You can get more laughter in your life with the following strategies:

•T.V. and Movies: There's no shortage of laughter opportunities from the entertainment, both at the theater and in the aisles of the video stores, as well as at home with T.V. comedies. While wasting your time watching something marginally funny may actually frustrate you, watching truly hilarious movies and shows is an easy way to get laughter into your life whenever you need it.

•Laugh With Friends: Going to a movie or comedy club with friends is a great way to get more laughter in your life. The contagious effects of laughter may mean you'll laugh more than you otherwise would have during the show, plus you'll have jokes to reference at later times. Having friends over for a party or game night is also a great setup for laughter and other good feelings. (See this article on laughing more for additional tips on getting more fun and laughter into your life.)

•Find Humor In Your Life: Instead of complaining about life's frustrations, try to laugh about them. If something is so frustrating or depressing it's ridiculous, realize that you could 'look back on it and laugh.' Think of how it will sound as a story you could tell to your friends, and then see if you can laugh about it now. With this attitude, you may also find yourself being more lighthearted and silly, giving yourself and those around you more to laugh about. Approach life in a more mirthful way and you'll find you're less stressed about negative events, and you'll achieve the health benefits of laughter. (See this article on maintaining a sense of humor.)

•'Fake It Until You Make It': Just as studies show the positive effects of smiling occur whether the smile is fake or real, faked laughter also provides the benefits mentioned above. The body can't distinguish between 'fake' laughter that you just start doing on purpose, and 'real' laughter that comes from true humor--the physical benefits are exactly the same, and the former usually leads to the latter anyway. So smile more, and fake laughter; you'll still achieve positive effects, and the fake merriment may lead to real smiles and laughter.

Why laughter may be the best way to warm up a relationship

So much of our attitude about life and our capacity to meet life's challenges depends on the quality of the relationships we have, especially our most intimate relationships that when they go sour, life tends to feel bleak. Because the quality of our relationships has a powerful effect on physical and mental balance, as well as our sense of satisfaction in life, it's important that we keep our relationships rewarding and fresh.

What can laughter do?

What Health Benefits of Laughter?!

Lower blood pressure

 Increase vascular blood flow and oxygenation of the blood

 Give a workout to the diaphragm and abdominal, respiratory, facial, leg, and back muscles

 Reduce certain stress hormones such as cortisol and adrenaline

Increase the response of tumor- and disease-killing cells such as Gamma-interferon and T-cells

Defend against respiratory infections–even reducing the frequency of colds–by immunoglobulin in saliva.

Raghda Sawas

Honey isn't Just Sugar!

Honey is so sweet and comforting that many people don’t give its healing abilities a second thought. The fact is, honey is far better than what most people perceive. Researchers are turning up more and more new evidence of honey's medical benefits in all directions. The benefits of honey don't just stop at satisfying the palate; honey also offers incredible antiseptic, antioxidant and cleansing properties for our body and health, hot beauty and skin care tips for ladies, and amazing healing properties as a head-to-toe remedy, from eye conjunctivitis to athlete foot. Its powerful healing attributes have long been used thousands of years ago and known to promote healing for cuts, cure ailments and diseases, and correct health disorders for generations after generations.

There are manyamazing health benefits of honey some of them are:

Nature's Energy Booster

The benefits of honey go beyond its great taste. A great natural source of carbohydrates which provide strength and energy to our bodies, honey is known for its effectiveness in instantly boosting the performance, endurance and reduce muscle fatigue of athletes. Its natural sugars play an important role in preventing fatigue during exercise. The glucose in honey is absorbed by the body quickly and gives an immediate energy boost, while the fructose is absorbed more slowly providing sustained energy.It is known that honey has also been found to keep levels of blood sugar fairly constant compared to other types of sugar.

The carbohydrates in honey helps to relieve the tiredness in your muscles and gives your body more energy to help you make it through the day better and help you be able to have a longer more active day without being so tired. Honey helps keep you from getting tired after exercising.

Try taking a spoonful of honey first to help give you more energy while exercising. To help your get through the morning, have some honey for your breakfast.

For Sore Throats

One of the better known health benefits of honey is that it is able to help treat sore throats.If you have a sore throat due to a cold or allergies, take a spoonful of honey to help soothe your sore throat. Honey can help kill bacteria in your system. Honey helps lower the inflammation in your throat. If you prefer instead of taking a teaspoon of honey, you can mix some honey with water or lemon and drink it to help soothe your sore throat.

Honey is Anti-Cancer!

 Honey can help prevent you from getting cancer; it can help lower the chances of getting forms of cancer. Honey does not get rid of cancer; it just helps you from getting cancer. Honey has antioxidants in them which are known as helping to aid in getting cancer. Be sure to include honey in your daily diet to help prevent forms of cancer.

Immunity System Builder

 Honey helps with your immune system. If your immune system is down, have some honey for breakfast. Try some on your toast, pancakes, waffles, or even just a spoonful has some honey for your lunch. Make yourself a peanut butter and honey sandwich. Honey helps your digestive system and helps you fight disease.

For Hangovers

When you get a hangover from drinking too much alcohol, combat its effects by applying honey remedy. Honey is gentle on the stomach and contains a mix of natural sugars such fructose which is known to speed up the oxidation of alcohol by the liver, acting as a 'sobering' agent. Follow this recipe: 15ml of liquid honey with 80ml of orange juice and 70ml of natural yogurt. Blend them together until smooth.

For Cuts and Burns

If you have a cut or a burn, try putting honey on it. Studies show that honey also reduces swelling and infection. Honey has antibacterial forms in it which helps in reducing bacteria in your body.

Raghda Sawas

Watercress, plenty of therapeutic properties

Watercress has plenty of health and therapeutic properties. However, due to its strong, pungent and bitter taste, it is never used alone, but is always added to juices, salads or other dishes as an ingredient, flavor or garnish.

Watercress has the following benefits:

Anti-anemic effect:  Watercress is particularly helpful in treating different types of anemia due to its high content in iron.  Iron is essential for the synthesis of hemoglobin, and folic acid, which plays a key role in the maturation of red cells in the bone marrow.  The right amount of vitamin C in watercress also makes better absorption of iron.

Anti-inflammatory properties:  Watercress is rich in vitamin C, which has an anti-inflammatory action and can help prevent or relieve the symptoms of cold, flu and other types of inflammation.

Anti-oxidant and anti-cancer effects:  Just as many other herbs, watercress is rich in anti-oxidants. Anti-oxidant substances help prevent or fight the damage caused by free radicals to body tissues, thereby contributing to prevent premature aging, as well as lower the risk of developing cancer and many other chronic or degenerative diseases.

Aphrodisiac effect:  Several historical sources show that watercress has been used for its aphrodisiac effect since the age of the ancient Romans and Persians.  This could be due to its high zinc and iron content.

Blood glucose:  Although not definitely proven, it seems that watercress can help control blood sugar levels and prevent or treat high blood glucose. It is probable that the hypoglycemic effect of watercress is in part due to its high content in soluble fiber, that helps reduce the absorption of carbohydrates from the intestine. This effect is particularly helpful for individuals with diabetes.

 Bone health:  The right proportion of calcium, magnesium, manganese, vitamins A, C and K in watercress helps promote and maintain healthy and strong bones.

Cough:  The sulphur glycosides found in watercress have been shown to modify bronchial secretions and exert an expectorant effect, which can be used to treat many forms of chronic bronchitis.

Digestive function:  Watercress does improve digestive function, due to its high content in vitamin C and fiber, which stimulate salivary and gastric secretions and the motility of the intestinal tract respectively.

DNA, preserve:  In a laboratory test, it was found that daily consumption of watercress increase the ability of cells to resist DNA damages to lymphocytes (white blood cells).

Eye health:  The high content in phytonutrients lutein and zeaxanthin are potent anti-oxidants;  together with vitamin A and zinc all in this herb help greatly improve eye health.

Hair health:  Watercress can be used topically to treat dandruff and prevent hair loss, due to its sulfur, iron, zinc and vitamin A content. The best results are obtained by rubbing the scalp and the hair with a watercress tincture.

Hangover:  A hangover happens when the liver gets overloaded with toxic alcohol.  Watercress juice is so concentrated with so much cleansing goodness that it activates the detoxifying enzymes in the liver for detoxifying a hangover.

Purifying effect:  Watercress has been used for centuries for its purifying effects. It enhances the diuresis and helps give the colon a good "spring-cleaning", thereby effectively removing toxins from the body.

Skin health:  When used topically, watercress juice can be helpful in relieving skin eczema, as well as other skin conditions.  Its high content of vitamin A and C best obtained by juicing are also beneficial for healthy skin.

 Thyroid gland:  The high iodine content in watercress can help prevent goitre, improve the function of the thyroid gland and relieve the symptoms of many forms of hypothyroidism.

Raghda Sawas